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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Radiation therapy to the chest

5

I.d Organizing pneumonia pattern (an area or areas of consolidation on imaging)

2
Last update : 13/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Radiation therapy (early effects)
5
Radiation therapy (endobronchial brachytherapy)
2
Radiation therapy (medium term & late effects)
5
Radiation therapy to the breast
4
Radiation therapy, infusional (injected 131I or 90Y radioactivity)
2
Radiation therapy, mantle-field-
5
Radiation therapy, stereotactic (SBRT)
5
Radioactive seeds
2

Publications

Relationship between radiation pneumonitis and organizing pneumonia after radiotherapy for breast cancer.
Radiation oncology (London, England) 2013 Mar 08;8;56 2013 Mar 08
Bronchoalveolar lavage in bronchiolitis obliterans organizing pneumonia primed by radiation therapy to the breast.
The Journal of allergy and clinical immunology 2000 Feb;105;239-44 2000 Feb
Migratory bronchiolitis obliterans organizing pneumonia after unilateral radiation therapy for breast carcinoma.
The European respiratory journal 1995 Feb;8;318-21 1995 Feb
Migratory organizing pneumonitis "primed" by radiation therapy.
The European respiratory journal 1995 Feb;8;322-6 1995 Feb

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