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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Radiation therapy (medium term & late effects)

5

XII.k Constrictive pericarditis - Pericardial thickening

2

Review at 24092234

Last update : 03/11/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Radiation therapy (early effects)
5
Radiation therapy to the breast
4
Radiation therapy to the chest
5
Radiation therapy, infusional (injected 131I or 90Y radioactivity)
2
Radiation therapy, mantle-field-
5
Radiation therapy, stereotactic (SBRT)
5

Publications

Effusive-constrictive pericarditis.
The New England journal of medicine 2004 Jan 29;350;469-75 2004 Jan 29
A case of refractory bilateral pleural effusion due to post-irradiation constrictive pericarditis.
Respirology (Carlton, Vic.) 2002 Dec;7;365-8 2002 Dec
Pathology of radiation-induced heart disease: a surgical and autopsy study of 27 cases.
Human pathology 1996 Aug;27;766-73 1996 Aug
Poor outcome in radiation-induced constrictive pericarditis.
International journal of radiation oncology, biology, physics 1993 Jan 15;25;329-31 1993 Jan 15
[Pericardiectomy: a challenge, a reality. The surgical experience of the Instituto Nacional de Cardiología "Ignacio Chávez"].
Archivos del Instituto de Cardiologia de Mexico 1993;63;403-6 1993

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