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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Radiation therapy (medium term & late effects)

5

IV.m Bronchial stenosis/stricture

3
Last update : 08/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Radiation therapy (early effects)
5
Radiation therapy to the breast
4
Radiation therapy to the chest
5
Radiation therapy, infusional (injected 131I or 90Y radioactivity)
2
Radiation therapy, mantle-field-
5
Radiation therapy, stereotactic (SBRT)
5

Publications

Bronchoscopic Manifestations of Airway Toxicity After Radiotherapy.
Clinical lung cancer 2018 Nov;19;e875-e878 2018 Nov
Fibrotic airway stenosis following radiotherapy in patients with adenoid cystic carcinoma.
Respirology (Carlton, Vic.) 2014 Aug;19;914-20 2014 Aug
Bronchial stenosis: an underreported complication of high-dose external beam radiotherapy for lung cancer?
International journal of radiation oncology, biology, physics 2005 Jan 01;61;64-9 2005 Jan 01
Radiation-induced bronchial stenosis: a new cause of platypnea-orthodeoxia.
Southern medical journal 1999 Jul;92;720-4 1999 Jul
Bronchial stenosis and sclerosing mediastinitis: an uncommon complication of external thoracic radiotherapy.
The European respiratory journal 1998 May;11;1188-90 1998 May

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