Pneumotox » Drug » Radiation therapy (medium term & late effects) » XII.b - Valvular heart disease and/or dysfunction

Radiation therapy (medium term & late effects)

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XII.b Valvular heart disease and/or dysfunction

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Review at PMID 24092234

Last update : 03/11/2013

Diagnosing DIRD

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Drug and radiation history

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Drug singularity - Correct identification of the drug

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Consistent timing of exposure v. onset of symptoms

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Clinical, imaging, BAL, pathological pattern consistent with the specific drug

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Careful exlusion of another cause

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Remission of symptoms with removal of drug

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Recurrence with rechallenge (rarely advisable)

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Causality assessment

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