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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Buprenorphine

2

XI.r Death following exposure or poisoning

1
Last update : 07/11/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Buprenorphine-Related Deaths in North Carolina from 2010 to 2018.
Journal of analytical toxicology 2021 Sep 17;45;780-791 2021 Sep 17
Buprenorphine may not be as safe as you think: a pediatric fatality from unintentional exposure.
Pediatrics 2012 Dec;130;e1700-3 2012 Dec

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