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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Paraquat

5

I.ba Irreversible respiratory damage requiring lung Tx

1
Last update : 06/08/2023
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Glyphosate
2

Publications

Case report: Lung transplantation for treatment of paraquat intoxication: timing of transplantation.
Frontiers in pharmacology 2023;14;1205689 2023

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