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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Opiates - Opioids - Opium

5

IX.i Respiratory arrest - Apnea

1
Last update : 26/11/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Antidotes
1
Body packing
4
Cannabinoids - Cannabinoid receptor agonists (synthetic) (K2, Spice)
5
Cannabis oil, paste, resin-H oil-Cannabidiol (inhaled)
1
Diacetylmorphine
1
Ethanol (ethyl alcohol, 'alcohol')
5
Fentanyl
5
Heroin (inhaled, insufflated, snorted)
4
Heroin (intravenous)
5
MT-45
1
Morphine
5
Naloxone
2
Opioids (synthetic)
5
Opium
1
Sufentanil
2
U-47700
1

Publications

Preventing Opioid-Induced Respiratory Depression in the Hospitalized Patient With Obstructive Sleep Apnea.
Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses 2018 Oct;33;601-607 2018 Oct
Opioids and Sleep-Disordered Breathing.
Chest 2016 Oct;150;934-944 2016 Oct
Three sudden postoperative respiratory arrests associated with epidural opioids in patients with sleep apnea.
Anesthesia and analgesia 1997 Aug;85;452-60 1997 Aug

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