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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Opiates - Opioids - Opium

5

XI.r Death following exposure or poisoning

2
Last update : 30/08/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Antidotes
1
Body packing
4
Cannabinoids - Cannabinoid receptor agonists (synthetic) (K2, Spice)
5
Cannabis oil, paste, resin-H oil-Cannabidiol (inhaled)
1
Diacetylmorphine
1
Ethanol (ethyl alcohol, 'alcohol')
5
Fentanyl
5
Heroin (inhaled, insufflated, snorted)
4
Heroin (intravenous)
5
MT-45
1
Morphine
5
Naloxone
2
Opioids (synthetic)
5
Opium
1
Sufentanil
2
U-47700
1

Publications

Fatal intoxication with new synthetic cannabinoids AMB-FUBINACA and EMB-FUBINACA.
Clinical toxicology (Philadelphia, Pa.) 2019 Nov;57;1103-1108 2019 Nov
Preventing Opioid-Induced Respiratory Depression in the Hospitalized Patient With Obstructive Sleep Apnea.
Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses 2018 Oct;33;601-607 2018 Oct
The Critical Care Crisis of Opioid Overdoses in the United States.
Annals of the American Thoracic Society 2017 Dec;14;1803-1809 2017 Dec
Contribution of opiates in sudden asthma deaths.
The American journal of forensic medicine and pathology 2015 Mar;36;49-52 2015 Mar
Postoperative opioid-induced respiratory depression: a closed claims analysis.
Anesthesiology 2015 Mar;122;659-65 2015 Mar
Opioid-induced respiratory depression in paediatrics: a review of case reports.
British journal of anaesthesia 2013 Feb;110;175-82 2013 Feb
A flood of opioids, a rising tide of deaths.
The New England journal of medicine 2010 Nov 18;363;1981-5 2010 Nov 18
Development of a coroner-based surveillance system for drug-related deaths in Los Angeles county.
Journal of urban health : bulletin of the New York Academy of Medicine 2010 Jul;87;656-69 2010 Jul
Underlying causes of cocaine, amphetamine and opioid related deaths in Australia.
Journal of clinical forensic medicine 2005 Aug;12;187-95 2005 Aug

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