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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Opiates - Opioids - Opium

5

II.a Pulmonary edema, noncardiogenic (NCPE)

2
Last update : 02/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Antidotes
1
Body packing
4
Cannabinoids - Cannabinoid receptor agonists (synthetic) (K2, Spice)
5
Cannabis oil, paste, resin-H oil-Cannabidiol (inhaled)
1
Diacetylmorphine
1
Ethanol (ethyl alcohol, 'alcohol')
5
Fentanyl
5
Heroin (inhaled, insufflated, snorted)
4
Heroin (intravenous)
5
MT-45
1
Morphine
5
Naloxone
2
Opioids (synthetic)
5
Opium
1
Sufentanil
2
U-47700
1

Publications

Fatal intoxication with new synthetic cannabinoids AMB-FUBINACA and EMB-FUBINACA.
Clinical toxicology (Philadelphia, Pa.) 2019 Nov;57;1103-1108 2019 Nov
Clinical images in medical toxicology: heroin overdose with non-cardiogenic pulmonary edema.
Clinical toxicology (Philadelphia, Pa.) 2006;44;399 2006
Thoracic complications of illicit drug use: an organ system approach.
Radiographics : a review publication of the Radiological Society of North America, Inc 2002 Oct;22 Spec No;S119-35 2002 Oct
Non-cardiogenic pulmonary edema after narcotic treatment for cancer pain.
Pain 1989 Dec;39;297-300 1989 Dec
Acute pulmonary edema following naloxone reversal of high-dose morphine anesthesia.
Anesthesiology 1977 Oct;47;376-8 1977 Oct

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