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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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FOLFOX chemotherapy regimen

3

I.a Pneumonitis (ILD), acute and/or severe (may cause ARDS)

1
Last update : 31/07/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Fluorouracil (5-FU)
3
Oxaliplatin-based regimens
4

Publications

Interstitial lung disease caused by oxaliplatin. An uncommon but not unknown complication.
Archivos de bronconeumologia 2017 Apr;53;213-215 2017 Apr
Cryptogenic organizing pneumonia during adjuvant chemotherapy with oxaliplatin, 5-fluorouracil, and leucovorin (FOLFOX) for colon cancer.
Journal of pharmacy practice 2013 Feb;26;62-6 2013 Feb

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