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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Bucillamine

1

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

1
Last update : 09/07/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

[A case of pulmonary infiltration with eosinophilia (PIE) syndrome induced by bucillamine treatment of rheumatoid arthritis].
Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 2002 Apr;40;321-5 2002 Apr
Eosinophilic bronchitis presenting with only severe dry cough due to bucillamine.
Respiratory medicine 1995 Mar;89;219-21 1995 Mar

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