Pneumotox Online
v2.2
  • RSS Feed
  • Contact
  • News
  • Diagnosing DIRD
  • Browse
  • Available on AppStore Available on AppStore

The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

  • Home
  • Browse by »
  • Drugs
  • Patterns

MTOR inhibitors

5

I.a Pneumonitis (ILD), acute and/or severe (may cause ARDS)

3
Last update : 25/09/2013
 
Search
Advanced search
Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Everolimus
5
Ridaforolimus
2
Sirolimus
4
Temsirolimus
2
Zotarolimus
1

Publications

A Fatal Case of Life-Threatening Interstitial Pneumonitis Induced by Everolimus for Metastatic Renal Cell Carcinoma: A Comment about the Increased Risk of Interstitial Lung Disease in Japanese.
Case reports in urology 2019;2019;2703871 2019
Complications of Lung Transplantation: A Roentgenographic Perspective.
Chest 2016 Jun;149;1535-45 2016 Jun
Mammalian target of rapamycin (mTOR) inhibitor-associated non-infectious pneumonitis in patients with renal cell cancer: predictors, management, and outcomes.
BJU international 2014 Mar;113;376-82 2014 Mar
Incidence and risk of pulmonary toxicity in patients treated with mTOR inhibitors for malignancy. A meta-analysis of published trials.
Acta oncologica (Stockholm, Sweden) 2012 Sep;51;873-9 2012 Sep
Incidence and management of mTOR inhibitor-associated pneumonitis in patients with metastatic renal cell carcinoma.
Annals of oncology : official journal of the European Society for Medical Oncology 2012 Aug;23;1943-1953 2012 Aug

Powered by

  • ^
  • Contact
  • Cookies
  • About