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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Bromocriptine

3

V.c Pleural thickening - Fibrothorax

2
Last update : 09/07/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Ergots, ergot alkaloids, ergolines
4

Publications

Cardiac and noncardiac fibrotic reactions caused by ergot-and nonergot-derived dopamine agonists.
Movement disorders : official journal of the Movement Disorder Society 2009 Jan 15;24;129-33 2009 Jan 15
Fibrosis associated with dopamine agonist therapy in Parkinson's disease.
Clinical neuropharmacology 2003;26;109-11 2003
Chronic constrictive pericarditis induced by long-term bromocriptine therapy: report of two cases.
The Annals of pharmacotherapy 1999 Oct;33;1050-4 1999 Oct
Pleuropulmonary disease as a side-effect of treatment with bromocriptine.
Respiratory medicine 1998 Sep;92;1172-4 1998 Sep
Pleural disease during treatment with bromocriptine in patients previously exposed to asbestos.
The European respiratory journal 1997 Dec;10;2711-5 1997 Dec
Suggestive evidence for bromocriptine-induced pleurisy.
The Netherlands journal of medicine 1996 Jun;48;232-6 1996 Jun
Bromocriptine and pleuropulmonary disease.
Archives of internal medicine 1989 Feb;149;258-9 1989 Feb
Pleuropulmonary disease during bromocriptine treatment of Parkinson's disease.
Archives of internal medicine 1988 Oct;148;2231-6 1988 Oct
Pleuropulmonary involvement during bromocriptine treatment.
Chest 1988 Nov;94;1034-6 1988 Nov
Pleuropulmonary reactions in patients on bromocriptine treatment.
European journal of respiratory diseases 1986 Jan;68;35-8 1986 Jan
[Pleuropulmonary fibrosis and bromocriptine].
La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris 1984 Mar 08;60;741-4 1984 Mar 08
Pleuropulmonary shadows on bromocriptine.
Lancet (London, England) 1981 Feb 07;1;323 1981 Feb 07

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