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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
Bromocriptine
3
V.c
Pleural thickening - Fibrothorax
2
Last update :
09/07/2012
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Ergots, ergot alkaloids, ergolines
Publications
Cardiac and noncardiac fibrotic reactions caused by ergot-and nonergot-derived dopamine agonists.
Fibrosis associated with dopamine agonist therapy in Parkinson's disease.
Chronic constrictive pericarditis induced by long-term bromocriptine therapy: report of two cases.
Pleuropulmonary disease as a side-effect of treatment with bromocriptine.
Pleural disease during treatment with bromocriptine in patients previously exposed to asbestos.
Suggestive evidence for bromocriptine-induced pleurisy.
Bromocriptine and pleuropulmonary disease.
Pleuropulmonary disease during bromocriptine treatment of Parkinson's disease.
Pleuropulmonary involvement during bromocriptine treatment.
Pleuropulmonary reactions in patients on bromocriptine treatment.
[Pleuropulmonary fibrosis and bromocriptine].
Pleuropulmonary shadows on bromocriptine.
