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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Silicone, fluid

5

I.al Silicone pneumonitis - 'Silicone lung'

3
Last update : 06/11/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Breast implants - Augmentation mammaplasty (w/wo evidence for leakage/rupture)
4

Publications

Pulmonary Empty Spaces: Silicone Embolism-A Decade of Increased Incidence and Its Histological Diagnosis.
Case reports in pathology 2016;2016;3741291 2016

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