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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Oxygen (dioxygen, O2)

4

II.a Pulmonary edema, noncardiogenic (NCPE)

1
Last update : 10/04/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Pulmonary edema associated with hyperbaric oxygen therapy.
Chest 2001 Oct;120;1407-9 2001 Oct
Oxygen toxicity in man. A prospective study in patients with irreversible brain damage.
The New England journal of medicine 1970 Dec 31;283;1478-84 1970 Dec 31
Pulmonary lesions associated with oxygen therapy and artificial ventilation.
The New England journal of medicine 1967 Feb 16;276;368-74 1967 Feb 16

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