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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Alemtuzumab

1

II.a Pulmonary edema, noncardiogenic (NCPE)

1
Last update : 30/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Acute pneumonitis and pericarditis related to alemtuzumab therapy in relapsing-remitting multiple sclerosis.
Journal of neurology 2017 Jan;264;168-169 2017 Jan
Isolated left-sided pulmonary edema caused by alemtuzumab (Campath) during kidney transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 2010 Aug;23;851-4 2010 Aug

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