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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Amlodipine

2

II.u Acute respiratory failure (e.g. from ARDS, ILD, PIE, OP, pulmonary edema or bronchospasm) requiring ECMO

1
Last update : 06/03/2020
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
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Clinical, imaging, BAL, pathological pattern consistent with the specific drug
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Careful exlusion of another cause
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Remission of symptoms with removal of drug
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Recurrence with rechallenge (rarely advisable)
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Causality assessment
More detailed checklist
See also under
Calcium channel blockers
3

Publications

The unknown known: non-cardiogenic pulmonary edema in amlodipine poisoning, a cohort study.
Clinical toxicology (Philadelphia, Pa.) 2020 Nov;58;1042-1049 2020 Nov
Extracorporeal therapy for amlodipine poisoning.
Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs 2020 Jun;23;183-186 2020 Jun

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