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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Amlodipine

2

XII.n Cardiovascular collapse - Cardiogenic shock - Hypotension

1
Last update : 26/12/2016
 
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Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
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Causality assessment
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See also under
Calcium channel blockers
3

Publications

Extracorporeal therapy for amlodipine poisoning.
Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs 2020 Jun;23;183-186 2020 Jun
Critical Management of Severe Hypotension Caused by Amlodipine Toxicity Managed With Hyperinsulinemia/Euglycemia Therapy Supplemented With Calcium Gluconate, Intravenous Glucagon and Other Vasopressor Support: Review of Literature.
Cardiology research 2018 Feb;9;46-49 2018 Feb
Recurrent episodes of life-threatening vasodilatory shock following unintentional intoxication with amlodipine.
Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 2017;58;369-371 2017

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