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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Amlodipine

2

II.b ARDS - Acute lung injury

1
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Calcium channel blockers
3

Publications

Amlodipine poisoning revisited: Acidosis, acute kidney injury and acute respiratory distress syndrome.
Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine 2014 Jul;18;467-9 2014 Jul
Amlodipine overdose.
The Annals of pharmacotherapy 1997;31;853-6 1997

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