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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Erlotinib

3

XVI.af Imaging: Lung cysts or bullae (see also XVI ah/bf)

1
Last update : 12/10/2014
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Tyrosine kinase inhibitors (EGFR) TKI
5

Publications

Atypical response to erlotinib in a patient with metastatic lung adenocarcinoma: a case report.
Journal of medical case reports 2014 Oct 09;8;335 2014 Oct 09
Bilateral pneumothorax complicating cystic metastases of bronchial squamous cell carcinoma under erlotinib.
Tumori 2013;99;e77-9 2013

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