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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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TNF-alpha antagonists / inhibitors

5

XVII.r Fungal infection (pulmonary/extrapulmonary)

2
Last update : 31/12/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Adalimumab
3
Etanercept
4
Golimumab
1
Infliximab
5

Publications

Case 9-2020: A 64-Year-Old Man with Shortness of Breath, Cough, and Hypoxemia.
The New England journal of medicine 2020 Mar 19;382;1150-1159 2020 Mar 19
Update on the diagnosis of pulmonary coccidioidomycosis.
Annals of the American Thoracic Society 2014 Feb;11;243-53 2014 Feb
Fungal infections complicating tumor necrosis factor alpha blockade therapy.
Mayo Clinic proceedings 2008 Feb;83;181-94 2008 Feb

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