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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Botulinum toxin (BOTOX)

1

IX.i Respiratory arrest - Apnea

1
Last update : 10/02/2015
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Case of iatrogenic botulism after botulinotherapy in clinical practice.
Terapevticheskii arkhiv 2018 Nov 22;90;102-104 2018 Nov 22
Botulism-like syndrome after injections of botulinum toxin.
Veterinary and human toxicology 2000 Jun;42;163 2000 Jun

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