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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Dasatinib

4

V.d Pleural/pericardial effusion, ANA positive (DI lupus)

1
Last update : 26/04/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Bosutinib
2
Imatinib
3
Ponatinib
2

Publications

Lupus-like symptoms with anti-RNP/Sm and anti-nuclear antibodies positivity: An extremely rare adverse event of dasatinib.
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 2020 Apr;26;738-741 2020 Apr
Dasatinib-induced lupus.
Lancet (London, England) 2008 Aug 30;372;713-4 2008 Aug 30

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