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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Cetuximab

4

XII.m Cardiac- cardiorespiratory/pulmonary arrest

1
Last update : 20/10/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Adverse events to monoclonal antibodies used for cancer therapy: Focus on hypersensitivity responses.
Oncoimmunology 2013 Oct 01;2;e26333 2013 Oct 01
Safety-related regulatory actions for biologicals approved in the United States and the European Union.
JAMA 2008 Oct 22;300;1887-96 2008 Oct 22
Safety and efficacy of cetuximab-chemotherapy combination in Saudi patients with metastatic colorectal cancer.
Indian journal of cancer 2007;44;56-61 2007

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