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Paracetamol - Acetaminophen

IV.a Bronchospasm - Wheezing - Asthma

Bronchospasm restricted to aspirin/NSAID-intolerant patients (PMID 7560658). Use of acetaminophen in asthmatic children regarded as safe (PMID 27532828)

Last update : 20/08/2016

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment

More detailed checklist

The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

Paracetamol - Acetaminophen

IV.a Bronchospasm - Wheezing - Asthma

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