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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Oxaliplatin-based regimens

4

I.b Pneumonitis (ILD)

1
Last update : 02/09/2017
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
FOLFOX chemotherapy regimen
3
Fluorouracil (5-FU)
3
Oxaliplatin
3

Publications

Oxaliplatin-related interstitial pneumonia with high-grade fever and relative bradycardia as the presenting signs: a case report.
Journal of medical case reports 2021 Apr 08;15;153 2021 Apr 08
Oxaliplatin-induced Pulmonary Toxicity: A Rare but Serious Complication.
Cureus 2020 Mar 31;12;e7483 2020 Mar 31
OXALIPLATIN INDUCED PULMONARY FIBROSIS: A CASE REPORT.
Acta clinica Croatica 2020 Dec;59;761-764 2020 Dec
Prognosis and treatment of FOLFOX therapy related interstitial pneumonia: a plea for multimodal immune modulating therapy in the respiratory insufficient patient.
BMC cancer 2017 Aug 29;17;586 2017 Aug 29

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