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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Oxaliplatin-based regimens

4

XV.c Path: Organizing pneumonia (OP/BOOP) pattern (see also Id)

1
Last update : 25/05/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
FOLFOX chemotherapy regimen
3
Fluorouracil (5-FU)
3
Oxaliplatin
3

Publications

Organizing pneumonia with fatal outcome after adjuvant chemotherapy with FOLFOX.
Archivos de bronconeumologia 2015 Nov;51;610 2015 Nov
Organizing pneumonia associated with oxaliplatin-combined chemotherapy: a case report.
Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2012;21;89-92 2012

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