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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Oxaliplatin-based regimens

4

I.d Organizing pneumonia pattern (an area or areas of consolidation on imaging)

1
Last update : 13/04/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
FOLFOX chemotherapy regimen
3
Fluorouracil (5-FU)
3
Oxaliplatin
3

Publications

Organizing pneumonia associated with oxaliplatin-combined chemotherapy: a case report.
Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2012;21;89-92 2012
Development of bronchiolitis obliterans organizing pneumonia with platinum-based chemotherapy for metastatic rectal cancer.
Clinical colorectal cancer 2010 Jul;9;177-8 2010 Jul
Cryptogenic organizing pneumonitis during oxaliplatin chemotherapy for colorectal cancer: case report.
Chest 2007 Dec;132;1997-9 2007 Dec

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