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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Oxaliplatin-based regimens

4

I.g Pulmonary fibrosis

1
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
FOLFOX chemotherapy regimen
3
Fluorouracil (5-FU)
3
Oxaliplatin
3

Publications

Oxaliplatin-induced Pulmonary Fibrosis: Two Case Reports.
Journal of the Korean Society of Coloproctology 2011 Oct;27;266-9 2011 Oct
Fatal pneumonitis induced by oxaliplatin.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2008 Nov;10;764-7 2008 Nov

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