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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Omalizumab

2

X.f Anaphylaxis-Anaphylactoid reaction (can be fatal)

2
Last update : 01/05/2012
 
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1
Drug and radiation history
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Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
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Publications

Anaphylactic risk related to omalizumab, benralizumab, reslizumab, mepolizumab, and dupilumab.
Clinical and translational allergy 2021 Jun;11;e12038 2021 Jun
Anaphylaxis to three humanized antibodies for severe asthma: a case study.
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 2020;16;46 2020
American Academy of Allergy, Asthma & Immunology/American College of Allergy, Asthma & Immunology Omalizumab-Associated Anaphylaxis Joint Task Force follow-up report.
The Journal of allergy and clinical immunology 2011 Jul;128;210-2 2011 Jul
Omalizumab: Practical considerations regarding the risk of anaphylaxis.
Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 2010 Dec 03;6;32 2010 Dec 03
Omalizumab-associated anaphylactic reactions reported between January 2007 and June 2008.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2009 Nov;103;442-5 2009 Nov
The use of omalizumab in the treatment of severe allergic asthma: A clinical experience update.
Respiratory medicine 2009 Aug;103;1098-113 2009 Aug
Delayed onset and protracted progression of anaphylaxis after omalizumab administration in patients with asthma.
The Journal of allergy and clinical immunology 2007 Dec;120;1378-81 2007 Dec
Systemic reaction to omalizumab.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2006 Aug;97;267 2006 Aug
Characterization of an anaphylactoid reaction to omalizumab.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2006 Apr;96;624-7 2006 Apr

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