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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Beta-2 agonists, B2 mimetics (parenteral)

3

XII.f Cardiomyopathy (acute, subacute, chronic)

1
Last update : 04/08/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Magnesium sulfate
1
Ritodrine
2
Salbutamol - Albuterol
3
Terbutaline (parenteral)
2
Tocolytic therapy
3

Publications

A case of apical ballooning syndrome in a male with status asthmaticus; highlighting the role of B2 agonists in the pathophysiology of a reversible cardiomyopathy.
Journal of community hospital internal medicine perspectives 2013;3; 2013
[Postpartum cardiomyopathy attributed to the use of beta-mimetics].
Annales francaises d'anesthesie et de reanimation 1983;2;86-8 1983

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