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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Temozolomide

2

XV.c Path: Organizing pneumonia (OP/BOOP) pattern (see also Id)

1
Last update : 26/05/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Temozolomide-Associated Organizing Pneumonia.
American journal of therapeutics 2022 Nov-Dec 01;29;e781-e783 2022 Nov-Dec 01
A fatal case of acute interstitial pneumonia (AIP) in a woman affected by glioblastoma.
Current drug safety 2014 Mar;9;73-6 2014 Mar
Temozolomide-associated bronchiolitis obliterans organizing pneumonia successfully treated with high-dose corticosteroid.
Journal of Korean medical science 2012 Apr;27;450-3 2012 Apr
Temozolomide-associated organizing pneumonitis.
Mayo Clinic proceedings 2007 Jun;82;771-3 2007 Jun

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