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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Piperacilline

1

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

1
Last update : 10/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Acute eosinophilic pneumonia due to piperacillin/tazobactam.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 2019 Mar;122;334-336 2019 Mar
Piperacillin-associated pulmonary infiltrates with eosinophilia: a case report.
Canadian respiratory journal 2010;17;e24-6 2010

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