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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Adalimumab

3

X.b Antiphospholipid antibodies w/wo the APL syndrome

1
Last update : 07/04/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
TNF-alpha antagonists / inhibitors
5

Publications

Antitumor necrosis factor alpha inhibitor-induced dermatomyositis and interstitial lung disease with anti-PL12 autoantibody: signs of antisynthetase syndrome.
The Journal of dermatology 2014 Nov;41;1034-6 2014 Nov
Adalimumab-associated antiphospholipid syndrome: a case report and review of the literature.
Clinical rheumatology 2013 Jul;32;1095-8 2013 Jul

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