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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Adalimumab

3

X.k Sarcoid-like granulomatosis (endo-/extrathoracic)

1
Last update : 12/03/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
TNF-alpha antagonists / inhibitors
5

Publications

A Case of Adalimumab-Induced Granulomatous Interstitial Nephritis.
Cureus 2021 Jun;13;e15986 2021 Jun
Granulomatous interstitial nephritis secondary to adalimumab therapy.
Clinical kidney journal 2018 Apr;11;219-221 2018 Apr
Adalimumab-induced pulmonary sarcoidosis not progressing upon treatment with etanercept.
Zeitschrift fur Rheumatologie 2017 May;76;372-374 2017 May
Pulmonary Sarcoidosis in Behçet's Disease Treated with Adalimumab.
European journal of case reports in internal medicine 2017;4;000576 2017
Adalimumab Induced Subcutaneous Nodular Sarcoidosis; A Rare Side Effect of Tumor Necrosis Factor-α Inhibitor.
Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG 2014 Oct 20;31;249-51 2014 Oct 20
Hemidiaphragm paresis and granulomatous pneumonitis associated with adalimumab: a case report.
Heart & lung : the journal of critical care 2014;43;84-6 2014
Sarcoid-like granulomatosis in patients treated with anti-TNFα factors. A case report and review of the literature.
Clinical rheumatology 2011 Apr;30;581-3 2011 Apr

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