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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Benzylthiouracil

1

X.s Vasculitis, pulmonary (w/wo AH), extrapulmonary, systemic: ANCA-positive

1
Last update : 09/07/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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Publications

Benzylthiouracil induced ANCA associated glomerulonephritis in patients with graves' disease.
La Tunisie medicale 2015 Nov;93;696-701 2015 Nov
[Benzylthiouracil induced ANCA-positive vasculitis].
La Tunisie medicale 2014 Jun;92;428-30 2014 Jun
[Benzylthiouracil-induced antineutrophil cytoplasmic antibody-associated cutaneous vasculitis: a case report and literature review].
La Revue de medecine interne 2013 Sep;34;561-4 2013 Sep
Benzylthiouracil-induced glomerulonephritis.
Case reports in medicine 2009;2009;687285 2009
[Benzylthiouracil induced ANCA-positive vasculitis: study of three cases and review of the literature].
Annales d'endocrinologie 2008 Dec;69;517-22 2008 Dec

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