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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Progesterone

2

I.c Eosinophilic pneumonia (pulmonary infiltrates and eosinophilia)

1
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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See also under
Oil-/lipid-based formulations (parenteral)
3
Sesame oil
1

Publications

Acute eosinophilic pneumonia with intramuscular progesterone after in vitro fertilization.
Fertility and sterility 2008 Oct;90;1200.e3-6 2008 Oct
Pneumonitis and eosinophilia after in vitro fertilization treatment.
Annals of emergency medicine 2006 May;47;472-5 2006 May
Acute eosinophilic pneumonia associated with intramuscular administration of progesterone as luteal phase support after IVF: case report.
Human reproduction (Oxford, England) 2004 Aug;19;1806-10 2004 Aug
Hypersensitivity to progesterone-in-oil after in vitro fertilization and embryo transfer.
Fertility and sterility 2003 Nov;80;1272-5 2003 Nov

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