Pneumotox Online
v2.2
  • RSS Feed
  • Contact
  • News
  • Diagnosing DIRD
  • Browse
  • Available on AppStore Available on AppStore

The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

  • Home
  • Browse by »
  • Drugs
  • Patterns

Benzocaine (incl. topical)

4

XIV.a Methemoglobinemia

4
Last update : 29/10/2023
 
Search
Advanced search
Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Anesthetic agents (local, topical)
3

Publications

Occult Methemoglobinemia in a Medically-Complex 7-Year-Old Child and the Opportunity for Pharmacist Intervention in Pediatric Emergency Medicine.
The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG 2024 Dec;29;650-653 2024 Dec
Case Report: An Uncommon Etiology of Vulvar Irritation and Swelling in an Adolescent Patient.
Journal of pediatric and adolescent gynecology 2022 Dec;35;715-717 2022 Dec
Benzocaine-related methaemoglobinemia after transoesophageal echocardiography: a rare, life-threatening complication.
BMJ case reports 2021 Apr 23;14; 2021 Apr 23
Topical Benzocaine and Methemoglobinemia.
American journal of therapeutics 2017;24;e596-e598 2017
An Uncommon Complication With Use of Topical Local Anesthetic Agents: Methemoglobinemia.
American journal of therapeutics 2016;23;e1968-e1969 2016
An Atypical Case of Methemoglobinemia due to Self-Administered Benzocaine.
Case reports in emergency medicine 2015;2015;670979 2015
Nosocomial Methemoglobinemia Resulting from Self-Administration of Benzocaine Spray.
Case reports in anesthesiology 2015;2015;685304 2015
Central cyanosis on a psychiatric unit treated at the Salford Royal Hospital.
Thorax 2014 Dec;69;1157-8 2014 Dec
Methemoglobinemia precipitated by benzocaine used during intubation.
Proceedings (Baylor University. Medical Center) 2014 Apr;27;133-5 2014 Apr
Methemoglobinemia with the use of benzocaine spray for awake fiberoptic intubation.
Middle East journal of anaesthesiology 2013 Oct;22;337-40 2013 Oct
Risk of acquired methemoglobinemia with different topical anesthetics during endoscopic procedures.
Local and regional anesthesia 2011;4;25-8 2011
A rare side effect of transesophageal echocardiography: methemoglobinemia from topical benzocaine anesthesia.
European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology 2008 Mar;9;289-90 2008 Mar
Benzocaine and lidocaine induced methemoglobinemia after bronchoscopy: a case report.
Journal of medical case reports 2008 Jan 23;2;16 2008 Jan 23
Intraoperative detection of methemoglobinemia in a patient given benzocaine spray to relieve discomfort from a nasogastric tube: a case report.
AANA journal 2008 Apr;76;99-102 2008 Apr
Topical benzocaine-induced methemoglobinemia in the pediatric population.
Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners 2008;22;335-9; quiz 340-1 2008
Benzocaine-induced methemoglobinemia based on the Mayo Clinic experience from 28 478 transesophageal echocardiograms: incidence, outcomes, and predisposing factors.
Archives of internal medicine 2007 Oct 08;167;1977-82 2007 Oct 08
Methemoglobinemia and benzocaine.
Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates 2007;30;342-5; quiz 346-7 2007
Methemoglobinemia-induced cardio-respiratory failure secondary to topical anesthesia.
American journal of therapeutics 2006;13;545-9 2006
Benzocaine-induced methemoglobinemia.
Anesthesia progress 2005;52;136-9 2005
Acquired methemoglobinemia: a retrospective series of 138 cases at 2 teaching hospitals.
Medicine 2004 Sep;83;265-273 2004 Sep
Reported adverse event cases of methemoglobinemia associated with benzocaine products.
Archives of internal medicine 2004 Jun 14;164;1192-6 2004 Jun 14
Critical rebound methemoglobinemia after methylene blue treatment: case report.
Pharmacotherapy 2004 Apr;24;538-40 2004 Apr
Benzocaine induced methemoglobinemia: a potentially fatal complication of transesophageal echocardiography.
Ochsner journal 2003;5;34-5 2003
Benzocaine-induced methemoglobinemia: a potentially fatal complication of transesophageal echocardiography.
Texas Heart Institute journal 2003;30;308-10 2003
Severe methemoglobinemia after transesophageal echocardiography.
American journal of therapeutics 2003;10;225-7 2003
Severe methemoglobinemia on reexposure to benzocaine.
Journal of clinical anesthesia 2001 Mar;13;128-30 2001 Mar
Severe methemoglobinemia from topical anesthetic spray: case report, discussion and qualitative systematic review.
CJEM 2001 Jan;3;51-6 2001 Jan
Unexpected cyanosis in the surgical patient.
Surgical endoscopy 2000 Jun;14;595 2000 Jun
Benzocaine-induced methemoglobinemia: report of a severe reaction and review of the literature.
The Annals of pharmacotherapy 1994 May;28;643-9 1994 May
Benzocaine-adultered street cocaine in association with methemoglobinemia.
Clinical chemistry 1992 Apr;38;596-7 1992 Apr

Powered by

  • ^
  • Contact
  • Cookies
  • About

The Pneumotox website uses cookies. By accessing or using our website, you consent to the collection, use and disclosure of the garnered information in accordance with our privacy policy.

Learn more about cookies