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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Nicardipine

1

II.a Pulmonary edema, noncardiogenic (NCPE)

1
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Nicardipine-associated pulmonary edema in a parturient: use of chest ultrasound.
International journal of obstetric anesthesia 2014 Aug;23;291-2 2014 Aug
Nicardipine-induced acute pulmonary edema: a rare but severe complication of tocolysis.
Case reports in critical care 2014;2014;242703 2014
[Acute pulmonary edema during preterm labor: role of nicardipine tocolysis (three cases)].
Journal de gynecologie, obstetrique et biologie de la reproduction 2005 Dec;34;807-12 2005 Dec
Pulmonary edema induced by calcium-channel blockade for tocolysis.
Anesthesia and analgesia 2004 Sep;99;910-911 2004 Sep

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