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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Oxytocin

2

IV.b Bronchospasm and angioedema

1
Last update : 02/05/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Oxytocin: an unexpected risk for cardiologic and broncho-obstructive effects, and allergic reactions in susceptible delivering women.
Multidisciplinary respiratory medicine 2013 Oct 20;8;67 2013 Oct 20
Bronchospasm and laryngeal stridor as an adverse effect of oxytocin treatment.
Critical care (London, England) 2003 Oct;7;392 2003 Oct

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