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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Oxytocin

2

II.a Pulmonary edema, noncardiogenic (NCPE)

2
Last update : 13/04/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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Publications

A case report on acute pulmonary edema induced by adverse drug event immediately after cesarean section.
International journal of surgery case reports 2025 Mar;128;110991 2025 Mar
Oxytocin-Induced Acute Pulmonary Edema: A Case Report and Literature Review.
Cureus 2021 May 16;13;e15067 2021 May 16
Fatal pulmonary oedema following oxytocin administration in a pregnant woman with acute myocardial infarction.
Cardiovascular toxicology 2011 Mar;11;74-7 2011 Mar
Acute pulmonary oedema following oxytocin administration: a life threatening complication.
Journal of the Indian Medical Association 2006 May;104;261-2 2006 May
Pulmonary edema possibly developing secondary to the intravenous administration of oxytocin.
Veterinary and human toxicology 1991 Dec;33;587-8 1991 Dec
Pulmonary edema during cesarean section related to the use of oxytocic drugs.
Acta anaesthesiologica Belgica 1984 Jun;35;155-64 1984 Jun
The cardiovascular effects of oxytocic drugs.
British journal of anaesthesia 1972 Aug;44;826-34 1972 Aug

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