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Diagnosing DIRD
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The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
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Drugs
Patterns
BCG therapy (topical instillations in the urinary bladder)
5
IX.ab
Guillain-Barré (or GB-like) syndrome (w/wo ARF)
1
Last update :
17/10/2018
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
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Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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Publications
Guillain Barré syndrome associated with bladder instillation of Bacille Calmette Guérin (BCG).