Pneumotox » Drug » BCG therapy (topical instillations in the urinary bladder) » V.a - Pleural effusion (uni- or bilateral) (can accompany DI-LDs)

BCG therapy (topical instillations in the urinary bladder)

Pleural effusion was not in isolation (PMID 24593234), but instead it was associated with BCG-induced ILD

Last update : 09/03/2014

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment