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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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BCG therapy (topical instillations in the urinary bladder)

5

XVI.u Imaging: A miliary pattern (diffuse random micronodules)

2
Last update : 08/11/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
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Publications

Complications of Intravesical BCG Immunotherapy for Bladder Cancer.
Radiographics : a review publication of the Radiological Society of North America, Inc 2019;39;80-94 2019
[Dyspnea after instillation therapy for bladder cancer].
Der Radiologe 2018 May;58;482-486 2018 May
Miliary Tuberculosis that Developed after Intravesical Bacillus Calmette-Guerin Therapy.
Internal medicine (Tokyo, Japan) 2017;56;1563-1567 2017
Subclinical miliary Mycobacterium bovis following BCG immunotherapy for transitional cell carcinoma of the bladder.
BMJ case reports 2014 May 08;2014; 2014 May 08
Miliary tuberculosis after intravesical bacille Calmette-Guérin immunotherapy for carcinoma of the bladder.
AJR. American journal of roentgenology 1999 Mar;172;748-50 1999 Mar
Miliary lung disease after intravesical bacillus Calmette-Guérin immunotherapy.
Radiology 1996 Oct;201;43-4 1996 Oct
T helper cell alveolitis after bacillus Calmette-Guerin immunotherapy for superficial bladder tumor.
The Journal of urology 1994 Jun;151;1634-7 1994 Jun

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