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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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BCG therapy (topical instillations in the urinary bladder)

5

X.l Systemic granulomatosis other than Xk

1
Last update : 12/10/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

[Bilateral Granulomatous Renal Masses after Intravesical BCG Therapy for Non-muscle-invasive Bladder Cancer and Carcinoma in Situ of the Upper Urinary Tract: A Case Study].
Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 2015 Jul;89;481-4 2015 Jul
Concurrent granulomatous hepatitis, pneumonitis and sepsis as a complication of intravesical BCG immunotherapy.
BMJ case reports 2013 Oct 10;2013; 2013 Oct 10

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