Pneumotox » Drug » BCG therapy (topical instillations in the urinary bladder) » XV.e - Path: ILD with a granulomatous component (see also Im)

BCG therapy (topical instillations in the urinary bladder)

With BCG, granulumas can be present in several organs and tissues. See: PMID 7053820

Last update : 07/10/2012

Diagnosing DIRD

Drug and radiation history

Drug singularity - Correct identification of the drug

Consistent timing of exposure v. onset of symptoms

Clinical, imaging, BAL, pathological pattern consistent with the specific drug

Careful exlusion of another cause

Remission of symptoms with removal of drug

Recurrence with rechallenge (rarely advisable)

Causality assessment