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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Anagrelide

2

I.a Pneumonitis (ILD), acute and/or severe (may cause ARDS)

1
Last update : 20/01/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Successful treatment by prednisolone for interstitial pneumonia associated with anagrelide in a patient with essential thrombocythemia.
International cancer conference journal 2017 Jan;6;22-24 2017 Jan
'Double hit' from streptococcal pneumonia and hypersensitivity pneumonitis associated with anagrelide.
Clinical and laboratory haematology 2006 Feb;28;63-5 2006 Feb
Severe hypersensitivity pneumonitis associated with anagrelide.
The Annals of pharmacotherapy 2003 Sep;37;1228-31 2003 Sep

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