v2.2
Contact
News
Diagnosing DIRD
Browse
Available on AppStore
The Drug-Induced Respiratory Disease Website
Philippe Camus, M.D.
Dijon, France
Browse by »
Drugs
Patterns
Trastuzumab
5
X.c
Capillary leak syndrome (CLS)
1
Last update :
17/10/2014
Search
Search
Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Trastuzumab deruxtecan
Trastuzumab emtansine (Ado-trastuzumab emtansine - TDM-1)
Publications
Trastuzumab-induced systemic capillary leak syndrome in a breast cancer patient.