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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Sufentanil

2

IV.e Cough (acute, violent, explosive)

1
Last update : 13/09/2012
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist

Publications

Dezocine prevents sufentanil-induced cough during general anesthesia induction: A randomized controlled trial.
Pharmacological reports : PR 2015 Feb;67;52-5 2015 Feb
Comparison of the incidence and severity of cough induced by sufentanil and fentanyl: a prospective, randomised, double-blind study.
Anaesthesia 2007 Dec;62;1230-2 2007 Dec
Small doses of sufentanil will produce violent coughing in young children.
Anesthesiology 1998 Jul;89;271-2 1998 Jul

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