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The Drug-Induced Respiratory Disease Website

Philippe Camus, M.D.

Dijon, France

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Imatinib

3

XVII.g Tuberculosis (pulmonary, pulmonary, extrapulmonary or disseminated). Reactivation or de novo

1
Last update : 23/10/2013
 
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Identify causative drugs
Diagnosing DIRD
1
Drug and radiation history
2
Drug singularity - Correct identification of the drug
3
Consistent timing of exposure v. onset of symptoms
4
Clinical, imaging, BAL, pathological pattern consistent with the specific drug
5
Careful exlusion of another cause
6
Remission of symptoms with removal of drug
7
Recurrence with rechallenge (rarely advisable)
8
Causality assessment
More detailed checklist
See also under
Bosutinib
2
Dasatinib
4
Nilotinib
2

Publications

Renal tuberculosis in an imatinib-treated chronic myeloid leukemia.
Jornal brasileiro de nefrologia 2020;42;366-369 2020
Tuberculous and non-tuberculous granulomatous lymphadenitis in patients receiving imatinib mesylate (glivec) for metastatic gastrointestinal stromal tumor.
Case reports in oncology 2013 Jan;6;134-42 2013 Jan
Tuberculosis complicating imatinib treatment for chronic myeloid leukaemia.
The European respiratory journal 2009 Mar;33;670-2 2009 Mar

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